Abstract:
Colorectal cancer (CRC) is among the most common types of cancer in the world. Globally a steadily
increasing proportion of elderly people in the world result in approximately 16 million new cases of cancer
by the year 2021. Regarding treatment; Meloxicam was shown to prevent the initiation of chemical-induced
tumors, and considered as anticancer agent by virtue of its anti-proliferative effect, capacity for cell cycle
arrest, and pro-apoptotic effects, also acted as free radical scavenger, in particular superoxide anion oxidation
scavenge. The aim of the current study was to clarify much important information on histopathology, histochemistry and immunoassay of CEA tumor marker characteristics of 1,2 DMH- induced colon tumor in
albino rat and its relationship with the aberrant crypt mucosa as precursor in colon cancer progression. The
study was carried out on 60 male albino rats, animals were divided into 5 groups; A: control gro