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Immunohistochemical Expression of Fn14 and GP88 as Prognostic Biological Markers in Invasive Human Breast Cancer

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dc.contributor.author Sabah, Ali Mugahed Al-Qadasi
dc.contributor.author Saeed, Mahmoud Saeed Mohamed
dc.contributor.author Roa, Mohmed Mahmoud Sultan
dc.date.accessioned 2023-01-04T09:18:45Z
dc.date.available 2023-01-04T09:18:45Z
dc.date.issued 2023-01-04
dc.identifier.uri http://dspacewku.repository.edu.sd/handle/123456789/2942
dc.description Scholars Journal of Applied Medical Sciences en_US
dc.description.abstract Fibroblast growth factor-inducible 14 (Fn14), is a member of the tumor necrosis factor receptor super family that normally expressed in healthy tissues, but its expression is increased in injured tissue where it thought to play role in tissue remodeling. Progranulin or acrogranin is an 88-kDa glycoprotein identified by a biological screen for protein targets associated with high tumorigenicity. The aim of the present work was to investigate the expression of Fn14 and GP88 as novel prognostic biomarkers in human invasive ductal carcinoma (IDC) versus benign tumors and normal breast tissues as well as their correlation with different pathological and histological parameters. Immunohistochemical technique was used to examine the expression of Fn14 and GP88 in normal, benign as well as in IDC. Present results showed higher expression of Fn14 and GP88 in IDC comparing to normal and benign breast en_US
dc.description.sponsorship جامعة غرب كردفان en_US
dc.language.iso other en_US
dc.publisher جامعة غرب كردفان en_US
dc.subject The aim of the present work en_US
dc.subject human invasive ductal carcinoma en_US
dc.subject histological parameters en_US
dc.title Immunohistochemical Expression of Fn14 and GP88 as Prognostic Biological Markers in Invasive Human Breast Cancer en_US
dc.type Other en_US


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