Abstract:
Equimolar amounts of imidazoleacetophenone and 2-aminobenzoic acid were combined
together and the Schiff base 4(1H-imidazole-yl)acetophenoneanthranilic acid was prepared
as a new bidentate complexing agent. The synthesized ligand was reacted with cobalt(II),
cadmium(II), and nickel(II) ions yielding air stable complexes. For quantification and
characterization purposes, elemental analysis, infrared spectra, electronic spectra, proton
nuclear magnetic resonance spectra and mass spectra studies were carried out on the
obtained complexes and ligand. Thermogravimetric analysis and magnetic susceptibility
measurements were also used for characterization. The ligand IR spectrum showed that the
ligand acts as a bidentate coordinates to the metal ions through the nitrogen and oxygen
atoms. Measurements of magnetic susceptibility for Ni(II) and Co(II) complexes were found
to be 3.4 and 3.8 B.M., respectively, in the range normal for the octahedral geometry. The
conductivity measurements revealed that the chelates are non-electrolytes. An in vitro
antimicrobial investigation was also carried out for the free ligand and its metal complexes
against a number of bacterial and fungal strains, to assess their antimicrobial properties by
diffusion technique. Antimicrobial activity of the prepared complexes showed higher activity
than the free ligand
